Saturday, April 4, 2015

Protein Energy Malnutrition PEM

 Protein Energy Malnutrition  PEM

Pediatric Nutrition course

 About 50% of the 10 million deaths among under-five children each year in the developing world are associated with malnutrition



 Protein energy malnutrition Definition:
   It is a range of pathological conditions arising from coincidental lack of proteins and calories, in varying proportions, occurring most frequently in infants and young children.
          PEM takes several forms
MARASMUS
          Marasmus is severe PEM characterized by body weight less than 60% of the average for age.
          It is mainly caused by inadequate but more or less balanced diet deficient in both proteins and calories.
          Clinical manifestations
          Growth failure:
    Weight is less than 60% of the expected average for age.
          Loss of subcutaneous fat:
    old face appearance.
          Muscle wasting:
          General: anxious look, irritable and have good appetite.
          Associated infections:
    UTI and Otitis Media
          Micronutrient deficiency:
    Iron deficiency anemia and vitamin A and D deficiencies may be present.
          Complications:
          Complication of diarrhea as dehydration and electrolyte disturbances.
          Infections: infection in Marasmus may have silent course with no fever.
          Hypoglycemia.
          Hypothermia.
          Mental sub normality.
          Prognosis
          Death rate: 1 – 2% of those who is severely that will need admission.
          Death occurs due to dehydration or infections.
          KWASHIORKOR
          Kwashiorkor is a sever form of PEM characterized by under weight between 60 – 80% of the expected average for age and edema
          It occurs mainly due to provision of inadequate, unbalanced diet, deficient mainly in proteins and consist mainly of carbohydrates
          It usually develops in the weaning and post-weaning period (The weanling dilemma)
          Clinical manifestations
          Under weight, weight between 60 –80% of the average for age.
          Edema. It is evident on the feet, lower parts of legs and dorsum of the hands. The cheeks become bulky, pale waxy in appearance.
          Subcutaneous fat is preserved.
          There is generalized muscle wasting.
          General: Miserable look, apathetic and not interested in the surroundings. There is anorexia and general weakness .
          MOON FACE.
          Hair changes: Hair is sparse, brittle and depigmented.
.
          SKIN DEPIGMENTATION.
          ANAEMIA
          Complications:
          Complications of diarrhea as dehydration and electrolyte disturbances.
          Infections.
          Hypothermia.
          Hypoglycemia
          Heart failure
          Marasmic Kwashiorkor
          Management
Initial Phase:
          Involves resuscitation, treatment of infection and correction of disordered metabolism. (electrolyte imbalance, specific deficiencies, hypoglycemia, hypothermia, dehydration, heart failure and shock)
          Bacterial infection must treated with broad spectrum antibiotics.
          supplements of vitamin A and folic acid are also recommended.
          Iron is contraindicated because of its potential toxicity and aggravation of infection
          Rehabilitation Phase
          Increased appetite and improvement of major abnormalities including loss of edema.
          The principles of management change to include feeding to appetite, stimulating emotional and physical development and preparing for home
          At this stage, the formula feed is changed to one that provides more energy and protein for growth
          supplementary iron is necessary during this phase for new hemoglobin synthesis.
Follow-Up Phase commences
          Home management, when the child has reached –1 SD weight-for-length or height, equivalent to 90% of WHO reference
          Ideally, the child is recalled or visited at increasing intervals for up to 3 years to ensure that recurrence of malnutrition is prevented and that healthy physical and mental development is promoted, supported and achieved.


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